Greater Neural Differentiation in the Ventral Visual Cortex Is Associated with Youthful Memory in Superaging.

ABSTRACT: Superagers are older adults who maintain youthful memory despite advanced age. Previous studies showed that superagers exhibit greater structural and intrinsic functional brain integrity, which contribute to their youthful memory. However, no studies, to date, have examined brain activity as superagers learn and remember novel information. Here, we analyzed functional magnetic resonance imaging data collected from 41 young and 40 older adults while they performed a paired associate visual recognition memory task. Superaging was defined as youthful performance on the long delay free recall of the California Verbal Learning Test. We assessed the fidelity of neural representations as participants encoded and later retrieved a series of word stimuli paired with a face or a scene image. Superag

SUBMITTER: Katsumi Y 

PROVIDER: S-EPMC8491682 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature