Non-Pharmaceutical Interventions and COVID-19 Burden in the United States.

ABSTRACT:

Background

Non-pharmaceutical interventions (NPIs) are mitigation strategies used to reduce the spread of transmissible diseases. The relative effectiveness of specific NPIs remains uncertain.

Methods

We used state-level Coronavirus disease 2019 (COVID-19) case and mortality data between January 19, 2020 and March 7, 2021 to model NPI policy effectiveness. Empirically derived breakpoints in case and mortality velocities were used to identify periods of stable, decreasing, or increasing COVID-19 burden. The associations between NPI adoption and subsequent decreases in case or death velocities were estimated using generalized linear models accounting for weekly variability shared across states. State-level NPI policies included: stay at home order, indoor public gathering ban

SUBMITTER: Ahlers MJ 

PROVIDER: S-EPMC8491859 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature