Association between chronic hepatitis B infection and COVID-19 outcomes: A Korean nationwide cohort study.

ABSTRACT:

Background/aims

We measured the association between underlying chronic hepatitis B (CHB) and antiviral use with infection rates among patients who underwent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

Methods

In total, 204,418 patients who were tested for SARS-CoV-2 between January and June 2020 were included. For each case patient (n = 7,723) with a positive SARS-CoV-2 test, random controls (n = 46,231) were selected from the target population who had been exposed to someone with coronavirus disease 2019 (COVID-19) but had a negative SARS-CoV-2 test result. We merged claim-based data from the Korean National Health Insurance Service database collected. Primary endpoints were SARS-CoV-2 infection and severe clinical outcomes of COVID-19.

Results<

SUBMITTER: Kang SH 

PROVIDER: S-EPMC8491877 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature