Phenotypic-dependent variability and the emergence of tolerance in bacterial populations.

ABSTRACT: Ecological and evolutionary dynamics have been historically regarded as unfolding at broadly separated timescales. However, these two types of processes are nowadays well-documented to intersperse much more tightly than traditionally assumed, especially in communities of microorganisms. Advancing the development of mathematical and computational approaches to shed novel light onto eco-evolutionary problems is a challenge of utmost relevance. With this motivation in mind, here we scrutinize recent experimental results showing evidence of rapid evolution of tolerance by lag in bacterial populations that are periodically exposed to antibiotic stress in laboratory conditions. In particular, the distribution of single-cell lag times-i.e., the times that individual bacteria from the community re

SUBMITTER: Camacho Mateu J 

PROVIDER: S-EPMC8492070 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature