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Association between Thyroid Dysfunction and Intensive Care Unit-Acquired Weakness: A Case-Control Study.


ABSTRACT:

Background

Thyroid disorders may decrease the threshold for developing myopathy. Nonthyroidal illness syndrome (NTIS) is a common form of thyroid dysfunction in critically ill patients who are prone to the development of intensive care unit-acquired weakness (ICUAW). We therefore tested the hypothesis that patients with abnormalities in thyroid function are at a higher risk of developing ICUAW.

Methods

We assessed blood samples from patients admitted to the ICU for ≥7 days for thyroid functions. Patients were classified into 4 categories (euthyroid, hyperthyroid, hypothyroid, and NTIS). Patients were then evaluated daily for ICUAW development. Patients with ICUAW were considered as cases, whereas patients who did not develop ICUAW served as controls. We compared demographic

SUBMITTER: Shabana TS 

PROVIDER: S-EPMC8492238 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature