Methadone and buprenorphine discontinuation among postpartum women with opioid use disorder.

ABSTRACT:

Background

The postpartum year is a vulnerable period for women with opioid use disorder, with increased rates of fatal and nonfatal overdose; however, data on the continuation of medications for opioid use disorder on a population level are limited.

Objective

This study aimed to examine the effect of discontinuing methadone and buprenorphine in women with opioid use disorder in the year following delivery and determine the extent to which maternal and infant characteristics are associated with time to discontinuation of medications for opioid use disorder.

Study design

This population-based retrospective cohort study used linked administrative data of 211,096 deliveries in Massachusetts between 2011 and 2014 to examine the adherence to medications for opioid use diso

SUBMITTER: Schiff DM 

PROVIDER: S-EPMC8492487 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature