Attachment of cartilage wear particles to the synovium negatively impacts friction properties.

ABSTRACT: Cartilage wear particles are released into the synovial fluid by mechanical and chemical degradation of the articular surfaces during osteoarthritis and attach to the synovial membrane. Accumulation of wear particles could alter key tissue-level mechanical properties of the synovium, hindering its characteristically low-friction interactions with underlying articular surfaces in the synovial joint. The present study employs a custom loading device to further the characterization of native synovium friction properties, while investigating the hypothesis that attachment of cartilage wear particles increases friction coefficient. Juvenile bovine synovium demonstrated characteristically low friction coefficients in sliding contact with glass, in agreement with historical measurements. Friction

SUBMITTER: Estell EG 

PROVIDER: S-EPMC8492547 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature