The application of tissue-engineered fish swim bladder vascular graft.
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ABSTRACT:
SUBMITTER: Bai H
PROVIDER: S-EPMC8492661 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
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The application of tissue-engineered fish swim bladder vascular graft.
Bai Hualong H Sun Peng P Wu Haoliang H Wei Shunbo S Xie Boao B Wang Wang W Hou Yachen Y Li Jing'an J Dardik Alan A Li Zhuo Z
Communications biology 20211005 1
Small diameter (< 6 mm) prosthetic vascular grafts continue to show very low long-term patency, but bioengineered vascular grafts show promising results in preclinical experiments. To assess a new scaffold source, we tested the use of decellularized fish swim bladder as a vascular patch and tube in rats. Fresh goldfish (Carassius auratus) swim bladder was decellularized, coated with rapamycin and then formed into patches or tubes for implantation in vivo. The rapamycin-coated patches showed decr ...[more]
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