Sex-Specific Differences in the Effect of Free Testosterone on Sarcopenia Components in Older Adults.

ABSTRACT:

Objective

The association of free testosterone (FT) with sarcopenia and its components is well known in men but incompletely understood in women. We examined the association of baseline FT with the prevalence and incidence of sarcopenia and its components in community-dwelling older adults.

Design

Cross-sectional and longitudinal analysis from the prospective population-based Korean Frailty and Aging Cohort Study.

Methods

A total of 1,879 community-dwelling older adults aged 70-84 years were enrolled for cross-sectional analysis and 1,583 subjects who participated in the 2-year follow-up survey were included for longitudinal analysis. Baseline FT levels was measured by radioimmunoassay. Skeletal muscle mass, handgrip strength, and physical performance tests were measu

SUBMITTER: Shin HE 

PROVIDER: S-EPMC8493256 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature