Origanum majorana L.: A Nutritional Supplement With Immunomodulatory Effects.

ABSTRACT: Origanum majorana L. is an aromatic herb that has been grown in several Mediterranean countries since ancient times, but became popular during the Middle Ages as a medicinal plant and seasoning ingredient. O. majorana has many pharmacological effects, but its immunoreactive components and mechanisms are still unclear. In this study, four compounds were isolated and identified from O. majorana by a spectral analysis, including ¹H and ¹³C-NMR. They were 1H-indole-2-carboxylic acid (1), (+)-laricresol (2), (+)-isolaricresol (3), and procumboside B (4, pB), which were isolated for the first time in O. majorana. The immunomodulatory effects of the four compounds were screened, and pB had good immunomodulatory activity

SUBMITTER: Wang S 

PROVIDER: S-EPMC8493290 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature