Normative placental structure in pregnancy using quantitative Magnetic Resonance Imaging.

ABSTRACT:

Introduction

To characterize normative morphometric, textural and microstructural placental development by applying advanced and quantitative magnetic resonance imaging (qMRI) techniques to the in-vivo placenta.

Methods

We enrolled 195 women with uncomplicated, healthy singleton pregnancies in a prospective observational study. Women underwent MRI between 16- and 40-weeks' gestation. Morphometric and textural metrics of placental growth were calculated from T2-weighted (T2W) images, while measures of microstructural development were calculated from diffusion-weighted images (DWI). Normative tables and reference curves were constructed for each measured index across gestation and according to fetal sex.

Results

Data from 269 MRI studies from 169 pregnant women were inc

SUBMITTER: Andescavage N 

PROVIDER: S-EPMC8493557 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature