Atherogenic index of plasma is associated with major adverse cardiovascular events in patients with type 2 diabetes mellitus.

ABSTRACT:

Background

Previous studies reported the prognostic value of the atherogenic index of plasma (AIP) in the course of atherosclerosis and other cardiovascular diseases (CVDs). Still, the predictive utility of the AIP is unknown among patients with type 2 diabetes mellitus (T2DM).

Methods

This was a secondary analysis of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study, which randomized 10,251 patients with long-lasting T2DM. ROC curve analysis was used to determine an optimal threshold for AIP, and the study population was divided into high and low AIP groups. Univariable and multivariable Cox proportional hazards regression analyses were used to determine the association between AIP and primary (major adverse cardiovascular events [MACEs], including nonfat

SUBMITTER: Fu L 

PROVIDER: S-EPMC8493717 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature