Incidence of osteoporosis and ambient air pollution in South Korea: a population-based retrospective cohort study.

ABSTRACT:

Background

This study investigated the associations between exposure to ambient air pollutants and the incidence of osteoporosis using the Korean National Insurance Service-National Sample Cohort.

Methods

This nationwide, population-based, retrospective cohort study included 237,149 adults aged ≥40 years that did not have a diagnosis of osteoporosis at baseline between January 1, 2003, and December 31, 2015. Osteoporosis was defined as claim codes and prescriptions of bisphosphonates or selective estrogen receptor modulators at least twice annually. After matching values for PM₁₀, NO₂, CO, and SO₂ during the 2002-2015 time period and PM_2.5 in 2015 with residential areas, the incidence of osteoporosis was analyzed using a Cox propor

SUBMITTER: Shin J 

PROVIDER: S-EPMC8493748 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature