No increased circular inference in adults with high levels of autistic traits or autism.

ABSTRACT: Autism spectrum disorders have been proposed to arise from impairments in the probabilistic integration of prior knowledge with sensory inputs. Circular inference is one such possible impairment, in which excitation-to-inhibition imbalances in the cerebral cortex cause the reverberation and amplification of prior beliefs and sensory information. Recent empirical work has associated circular inference with the clinical dimensions of schizophrenia. Inhibition impairments have also been observed in autism, suggesting that signal reverberation might be present in that condition as well. In this study, we collected data from 21 participants with self-reported diagnoses of autism spectrum disorders and 155 participants with a broad range of autistic traits in an online probabilistic decision-mak

SUBMITTER: Angeletos Chrysaitis N 

PROVIDER: S-EPMC8494311 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature