Predictors of adherence and persistence to disease-modifying therapies in Multiple Sclerosis.

ABSTRACT:

Background and aims

In multiple sclerosis (MS), non-adherence/non-persistence is related to suboptimal response to treatment, including disease relapses and the need for more expensive healthcare. The aim of this study was to identify predictors related to adherence to disease modifying therapies (DMTs) in a cohort of Argentinian MS patients.

Methods

We conducted a cross-sectional study at the National Medical Care Program from Argentina. MS patients with at least one claim for a DMT from 1 January 2017 to 1 October 2017 were identified. A telephone survey was performed to assess clinical and demographic factors. The medication possession ratio (MPR) was used to estimate adherence; MPR <80% defined non-adherence. Associations were studied using a logistic regression model.

SUBMITTER: Zanga G 

PROVIDER: S-EPMC8495537 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature