Association Between Brain Volumes and Patterns of Physical Activity in Community-Dwelling Older Adults.

ABSTRACT:

Background

Larger brain volumes are often associated with more free-living physical activity (PA) in cognitively normal older adults. Yet, whether greater brain volumes are associated with more favorable (less fragmented) PA patterns, and whether this association is stronger than with total PA, remains unknown.

Methods

Brain magnetic resonance imaging and wrist-worn accelerometer data were collected in 301 participants (mean age = 77 [SD = 7] years, 59% women) enrolled in the Baltimore Longitudinal Study of Aging. Linear regression models were fit to examine whether brain volumes (cc) were cross-sectionally associated with: (a) total daily PA minutes and (b) activity fragmentation (mean number of PA bouts / total PA minutes × 100). Sensitivity analyses were conducted by adju

SUBMITTER: Wanigatunga AA 

PROVIDER: S-EPMC8495900 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature