Right-left ventricular shape variations in tetralogy of Fallot: associations with pulmonary regurgitation.

ABSTRACT:

Background

Relationships between right ventricular (RV) and left ventricular (LV) shape and function may be useful in determining optimal timing for pulmonary valve replacement in patients with repaired tetralogy of Fallot (rTOF). However, these are multivariate and difficult to quantify. We aimed to quantify variations in biventricular shape associated with pulmonary regurgitant volume (PRV) in rTOF using a biventricular atlas.

Methods

In this cross-sectional retrospective study, a biventricular shape model was customized to cardiovascular magnetic resonance (CMR) images from 88 rTOF patients (median age 16, inter-quartile range 11.8-24.3 years). Morphometric scores quantifying biventricular shape at end-diastole and end-systole were computed using principal component analy

SUBMITTER: Mauger CA 

PROVIDER: S-EPMC8496085 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature