Codon usage bias and dinucleotide preference in 29 Drosophila species.

ABSTRACT: Codon usage bias, where certain codons are used more frequently than their synonymous counterparts, is an interesting phenomenon influenced by three evolutionary forces: mutation, selection, and genetic drift. To better understand how these evolutionary forces affect codon usage bias, an extensive study to detect how codon usage patterns change across species is required. This study investigated 668 single-copy orthologous genes independently in 29 Drosophila species to determine how the codon usage patterns change with phylogenetic distance. We found a strong correlation between phylogenetic distance and codon usage bias and observed striking differences in codon preferences between the two subgenera Drosophila and Sophophora. As compared to the subgenus Sophophora, species of the subgenu

SUBMITTER: Kokate PP 

PROVIDER: S-EPMC8496323 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature