Clinical features and diagnosis of multiple myeloma: a population-based cohort study in primary care.

ABSTRACT:

Objectives

Patients with multiple myeloma (MM) experience significant delays in diagnosis due to non-specific symptomatology. The aim of this study was to characterise the frequency and timing of clinical features in the primary care setting prior to MM diagnosis.

Design

Population-based cohort study.

Setting

Electronic health records data of approximately 17 million patients (2006-2016) within the UK Clinical Practice Research Datalink.

Participants

Patients aged ≥18 years with newly diagnosed MM (NDMM), no history of solid tumours and ≥2 years registration in a primary care practice prior to MM diagnosis.

Main outcome measures

Clinical features and symptoms including bone pain, skeletal-related events (SREs), investigation and confirmation of MM diagno

SUBMITTER: Seesaghur A 

PROVIDER: S-EPMC8496401 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature