Flexible, high-resolution thin-film electrodes for human and animal neural research.

ABSTRACT: Objective.Brain functions such as perception, motor control, learning, and memory arise from the coordinated activity of neuronal assemblies distributed across multiple brain regions. While major progress has been made in understanding the function of individual neurons, circuit interactions remain poorly understood. A fundamental obstacle to deciphering circuit interactions is the limited availability of research tools to observe and manipulate the activity of large, distributed neuronal populations in humans. Here we describe the development, validation, and dissemination of flexible, high-resolution, thin-film (TF) electrodes for recording neural activity in animals and humans.Approach.We leveraged standard flexible printed-circuit manufacturing processes to build high-res

SUBMITTER: Chiang CH 

PROVIDER: S-EPMC8496685 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature