Antimicrobial activity of hemodialysis catheter lock solutions in relation to other compounds with antiseptic properties.

ABSTRACT: Proper protection of vascular access after haemodialysis is one of the key measures for the prevention of catheter-related infections. Various substances with bactericidal and anticoagulant properties are used to fill catheters, but due to the unsatisfactory clinical effects and occurrence of adverse reactions, the search for new substances is still ongoing. In the present paper, we compared the in vitro antimicrobial activity of solutions used for tunnelled catheter locking (taurolidine, trisodium citrate) and solutions of substances that could potentially be used for this purpose (sodium bicarbonate, polyhexanide-betaine). The studies have been conducted on bacteria that most commonly cause catheter-related infections. The values of both minimum inhibitory concentration and minimum biofi

SUBMITTER: Piatkowska E 

PROVIDER: S-EPMC8496847 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature