Convergent and divergent brain structural and functional abnormalities associated with developmental dyslexia.

ABSTRACT: Brain abnormalities in the reading network have been repeatedly reported in individuals with developmental dyslexia (DD); however, it is still not totally understood where the structural and functional abnormalities are consistent/inconsistent across languages. In the current multimodal meta-analysis, we found convergent structural and functional alterations in the left superior temporal gyrus across languages, suggesting a neural signature of DD. We found greater reduction in grey matter volume and brain activation in the left inferior frontal gyrus in morpho-syllabic languages (e.g. Chinese) than in alphabetic languages, and greater reduction in brain activation in the left middle temporal gyrus and fusiform gyrus in alphabetic languages than in morpho-syllabic languages. These language

SUBMITTER: Yan X 

PROVIDER: S-EPMC8497057 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature