Effect of a strategy of comprehensive vasodilation versus usual care on health-related quality of life among patients with acute heart failure.

ABSTRACT:

Aims

We aimed to assess the long-term effect of a strategy of comprehensive vasodilation versus usual care on health-related quality of life (HRQL) among patients with acute heart failure (AHF).

Methods and results

Health-related quality of life was prospectively assessed by the generic 3-levelled EQ-5D and the disease-specific Kansas City Cardiomyopathy Questionnaire (KCCQ) among adult AHF patients enrolled in an international, multicentre, randomised, open-label blinded-end-point trial of a strategy that emphasized early intensive and sustained vasodilation using maximally tolerated doses of established oral and transdermal vasodilators according to systolic blood pressure. Changes in EQ-5D and KCCQ from admission to 180 day follow-up were individually compared between the

SUBMITTER: Belkin M 

PROVIDER: S-EPMC8497201 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature