Blood pressure visit-to-visit variability and outcomes in patients with heart failure with preserved ejection fraction.

ABSTRACT:

Aims

Previous studies report that blood pressure (BP) variability is associated with increased risk of adverse outcomes in patients diagnosed with cardiovascular disease. However, studies have not fully explored this association in patients with heart failure with preserved ejection fraction (HFpEF). This study sought to explore the association between visit-to-visit variability (VVV) of BP and clinical outcomes in patients with HFpEF.

Methods and results

A total of 1988 patients (mean age of 67.73 ± 9.22, 51.7% female) from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial were included in this study. BP-VVV was determined by standard deviation (SD) of mean systolic BP (SBP-SD) from six measurements (baseline and months

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC8497211 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature