Right ventricular hemodynamics and performance in relation to perfusion during first year after heart transplantation.

ABSTRACT:

Aims

We aim to evaluate changes in invasive haemodynamics, right ventricular (RV) function, and perfusion during the first year after heart transplantation (HTx) and to determine the relation between RV function and myocardial perfusion.

Methods and results

Thirty patients were prospectively enrolled at the time of HTx. Right heart catheterization (RHC), comprehensive 2D and 3D echocardiography and cardiac biomarkers were performed at baseline (≤2 weeks after HTx) and at follow-up 1, 3, 6, and 12 months after HTx. At 12 months, HTx patients were subjected to an exercise stress test with assessment of maximal oxygen consumption (VO₂ max). RV myocardial perfusion reserve was evaluated by ¹⁵ O-H₂ O positron emission tomography at baseline and at

SUBMITTER: Clemmensen TS 

PROVIDER: S-EPMC8497213 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature