Effects of inspiratory muscle training combined with aerobic exercise training on neurovascular control in chronic heart failure patients.

ABSTRACT:

Aims

We tested the hypothesis that the effects of combined inspiratory muscle training and aerobic exercise training (IMT + AET) on muscle sympathetic nerve activity (MSNA) and forearm blood flow in patients with heart failure with reduced ejection fraction are more pronounced than the effects of AET alone.

Methods and results

Patients aged 30-70 years, New York Heart Association Functional Class II-III, and left ventricular ejection fraction ≤40% were randomly assigned to four groups: IMT (n = 11), AET (n = 12), IMT + AET (n = 9), and non-training (NT; n = 10). MSNA was recorded using microneurography. Forearm blood flow was measured by venous occlusion plethysmography and inspiratory muscle strength by maximal inspiratory pressure. IMT consisted of 30 min sessions, five ti

SUBMITTER: Trevizan PF 

PROVIDER: S-EPMC8497326 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature