Abnormal P-wave terminal force in lead V₁ is a marker for atrial electrical dysfunction but not structural remodelling.

ABSTRACT:

Aims

There is a lack of diagnostic and therapeutic options for patients with atrial cardiomyopathy and paroxysmal atrial fibrillation. Interestingly, an abnormal P-wave terminal force in electrocardiogram lead V₁ (PTFV₁ ) has been associated with atrial cardiomyopathy, but this association is poorly understood. We investigated PTFV₁ as a marker for functional, electrical, and structural atrial remodelling.

Methods and results

Fifty-six patients with acute myocardial infarction and 13 kidney donors as control cohort prospectively underwent cardiac magnetic resonance imaging to evaluate the association between PTFV₁ and functional remodelling (atrial strain). To further investigate underlying pathomechanisms, right atrial appendage b

SUBMITTER: Lebek S 

PROVIDER: S-EPMC8497361 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature