Clinical outcomes of modifying hypertension treatment intensity in older adults treated to low blood pressure.

ABSTRACT:

Background/objectives

Hypertension treatment reduces cardiovascular events. However, uncertainty remains about benefits and harms of deintensification or further intensification of antihypertensive medication when systolic blood pressure (SBP) is tightly controlled in older multimorbid patients, because of their frequent exclusion in trials. We assessed the association of hypertension treatment deintensification or intensification with clinical outcomes in older adults with tightly controlled SBP.

Design

Longitudinal cohort study (2011-2013) with 9-month follow-up.

Setting

U.S.-nationwide primary care Veterans Health Administration healthcare system.

Participants

Veterans aged 65 and older with baseline SBP <130 mmHg and ≥1 antihypertensive medication during ≥2

SUBMITTER: Aubert CE 

PROVIDER: S-EPMC8497391 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature