Persistence and clearance of high-risk human papillomavirus and cervical dysplasia at 1 year in women living with human immunodeficiency virus: a prospective cohort study.

ABSTRACT:

Objective

Evaluate 1-year outcomes of cervical cancer screening and treatment using primary high-risk human papillomavirus (HPV) testing in women living with human immunodeficiency virus (HIV).

Design

Prospective cohort study.

Setting

HIV treatment centre in Botswana.

Population

Women living with HIV.

Methods

Participants underwent cervical cancer screening with high-risk HPV testing and triage evaluation at baseline and 1-year follow up. Excisional treatment was offered as indicated. Histopathology was the reference standard.

Main outcome measures

Persistence, clearance and incidence of high-risk HPV infection; and persistence, progression, regression, cure and incidence of cervical dysplasia.

Results

Among 300 women screened at baseline,

SUBMITTER: Luckett R 

PROVIDER: S-EPMC8497414 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature