Decreased frontotemporal connectivity in patients with parkinson's disease experiencing face pareidolia.

ABSTRACT: The precise neural underpinnings of face pareidolia in patients with Parkinson's disease (PD) remain unclear. We aimed to clarify face recognition network abnormalities associated with face pareidolia in such patients. Eighty-three patients with PD and 40 healthy controls were recruited in this study. Patients with PD were classified into pareidolia and nonpareidolia groups. Volumetric analyses revealed no significant differences between the pareidolia (n = 39) and nonpareidolia (n = 44) patient groups. We further observed decreased functional connectivity among regions of interest in the bilateral frontotemporal lobes in patients with pareidolia. Seed-based analysis using bilateral temporal fusiform cortices as seeds revealed significantly decreased connectivity with the bilateral inferio

SUBMITTER: Kajiyama Y 

PROVIDER: S-EPMC8497472 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature