Risk of second cancer among young prostate cancer survivors.

ABSTRACT:

Purpose

About 40% of men diagnosed with prostate cancer (Pca) are ≤65 years of age. This study evaluates the risk of second cancer among young Pca patients treated with surgery or radiation.

Materials and methods

This is a retrospective review of 150,915 men aged ≤65 years at Pca diagnosis treated with surgery or radiation registered in the Surveillance, Epidemiology, and End Results (SEER) database between 1973 and 2014. Incidence rates of second rectum/rectosigmoid junction (RJ), bladder, and lung cancer in each treatment group were reported with adjustment for potential confounders. Cumulative incidence functions were used to summarize the risk of second cancer after completing initial treatment.

Results

Men treated with external beam radiation (BEAM), brachytherap

SUBMITTER: Zhang H 

PROVIDER: S-EPMC8497857 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature