Barrett's esophagus surveillance in a prospective Dutch multi-center community-based cohort of 985 patients demonstrates low risk of neoplastic progression.

ABSTRACT:

Background and aims

Barrett's esophagus (BE) is accompanied by an increased risk of developing esophageal cancer. Accurate risk-stratification is warranted to improve endoscopic surveillance. Most data available on risk factors is derived from tertiary care centers or from cohorts with limited surveillance time or surveillance quality. The aim of this study was to assess endoscopic and clinical risk factors for progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) in a large prospective cohort of BE patients from community hospitals supported by an overarching infrastructure to ensure optimal surveillance quality.

Methods

A well-defined prospective multicenter cohort study was initiated in six community hospitals in the Amsterdam region in 2003. BE pat

SUBMITTER: Klaver E 

PROVIDER: S-EPMC8498404 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature