Moderate-Intensity Physical Exercise Affects the Exercise Performance and Gut Microbiota of Mice.

ABSTRACT: The gut microbiota is closely associated with the health of the host and is affected by many factors, including exercise. In this study, we compared the gut microbial changes and exercise performance over a 14-week period in mice that performed exercise (NE; n = 15) and mice that did not perform exercise (NC; n = 15). Mice were subjected to stool collection and exercise tests one week prior to adaptive training and after 2, 6, 10, and 14 weeks of exercise. Bacteria associated with the stool samples were assessed via Illumina-based 16S rRNA gene sequencing. While there was no significant difference in body weight between the groups (p > 0.05), the NE group had a significantly higher exercise performance from weeks 2-14 (p < 0.01) and lower fat coefficient (p < 0.01) compared with the

SUBMITTER: Yang W 

PROVIDER: S-EPMC8498591 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature