Fast 3D MR elastography of the whole brain using spiral staircase: Data acquisition, image reconstruction, and joint deblurring.

ABSTRACT:

Purpose

To address the need for a method to acquire 3D data for MR elastography (MRE) of the whole brain with substantially improved spatial resolution, high SNR, and reduced acquisition time compared with conventional methods.

Methods

We combined a novel 3D spiral staircase data-acquisition method with a spoiled gradient-echo pulse sequence and MRE motion-encoding gradients (MEGs). The spiral-out acquisition permitted use of longer-duration motion-encoding gradients (ie, over two full oscillatory cycles) to enhance displacement SNR, while still maintaining a reasonably short TE for good phase-SNR. Through-plane parallel imaging with low noise penalties was implemented to accelerate acquisition along the slice direction. Shared anatomical information was exploited in the deb

SUBMITTER: Peng X 

PROVIDER: S-EPMC8498799 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature