Strategies to Prevent Acute Kidney Injury after Pediatric Cardiac Surgery: A Network Meta-Analysis.

ABSTRACT:

Background and objectives

AKI is a common complication after pediatric cardiac surgery and has been associated with higher morbidity and mortality. We aimed to compare the efficacy of available pharmacologic and nonpharmacologic strategies to prevent AKI after pediatric cardiac surgery.

Design, setting, participants, & measurements

PubMed/MEDLINE, Embase, Cochrane Controlled Trials Register, and reference lists of relevant articles were searched for randomized controlled trials from inception until August 2020. Random effects traditional pairwise, Bayesian network meta-analyses, and trial sequential analyses were performed.

Results

Twenty randomized controlled trials including 2339 patients and 11 preventive strategies met the eligibility criteria. No overall signific

SUBMITTER: Van den Eynde J 

PROVIDER: S-EPMC8498996 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature