Case report of the first cured patient with Mycobacterium Chimaera infection following cardiac valve replacement in the mainland of China.

ABSTRACT:

Background

Mycobacterium chimaera infections subsequent to cardiac surgery are related to contaminated heater-cooler devices, with high mortality. Nevertheless, few studies have been reported in Asia.

Case presentation

We described the case of a 55-year-old man with Mycobacterium chimaera infection following cardiac surgery in the mainland of China. He was diagnosed with endocarditis caused by Mycobacterium chimaera subsequent to open heart surgery. Metagenomic next-generation sequencing (mNGS) and 16S rRNA gene PCR analysis were used to identify potential pathogens. The patient underwent redo valve replacement surgery and received combination therapy with azithromycin, ethambutol, linezolid, and amikacin. No signs of relapse were observed during the 11-month follow-up visit

SUBMITTER: Lu D 

PROVIDER: S-EPMC8499553 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature