Comparative frequency and prognostic impact of myocardial injury in hospitalized patients with COVID-19 and Influenza.

ABSTRACT:

Aims

Myocardial injury (MINJ) in Coronavirus disease 2019 (COVID-19) identifies individuals at high mortality risk but its clinical relevance is less well established for Influenza and no comparative analyses evaluating frequency and clinical implications of MINJ among hospitalized patients with Influenza or COVID-19 are available.

Methods and results

Hospitalized adults with laboratory confirmed Influenza A or B or COVID-19 underwent highly sensitive cardiac T Troponin (hs-cTnT) measurement at admission in four regional hospitals in Canton Ticino, Switzerland. MINJ was defined as hs-cTnT >14 ng/L. Clinical, laboratory and outcome data were retrospectively collected. The primary outcome was mortality up to 28 days. Cox regression models were used to assess correlations betwe

SUBMITTER: Biasco L 

PROVIDER: S-EPMC8499788 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature