False Coronavirus Disease 2019 Cases due to Contamination by Inactivated Virus Vaccine.

ABSTRACT: A false-positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse-transcription polymerase chain reaction result can lead to unnecessary public health measures. We report 2 individuals whose respiratory specimens were contaminated by an inactivated SARS-CoV-2 vaccine strain (CoronaVac), likely at vaccination premises. Incidentally, whole genome sequencing of CoronaVac showed adaptive deletions on the spike protein, which do not result in observable changes of antigenicity.

SUBMITTER: To KK 

PROVIDER: S-EPMC8499976 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature