Phrenic nerve stimulation prevents diaphragm atrophy in patients with respiratory failure on mechanical ventilation.

ABSTRACT:

Background

Diaphragm atrophy and dysfunction is a major problem among critically ill patients on mechanical ventilation. Ventilator-induced diaphragmatic dysfunction is thought to play a major role, resulting in a failure of weaning. Stimulation of the phrenic nerves and resulting diaphragm contraction could potentially prevent or treat this atrophy. The subject of this study is to determine the effectiveness of diaphragm stimulation in preventing atrophy by measuring changes in its thickness.

Methods

A total of 12 patients in the intervention group and 10 patients in the control group were enrolled. Diaphragm thickness was measured by ultrasound in both groups at the beginning of study enrollment (hour 0), after 24 hours, and at study completion (hour 48). The obtained data

SUBMITTER: Sotak M 

PROVIDER: S-EPMC8500254 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature