Changes in serum uric acid levels as a predictor of future decline in renal function in older adults with type 2 diabetes.

ABSTRACT:

Abstract

Given that factors affecting renal function remain unknown, this study aimed to identify key predictors of estimated glomerular filtration rate (eGFR) deterioration, which is a representative of renal function decline in older adults with type 2 diabetes (T2DM). In an exploratory prospective observational study, we enrolled 268 Japanese people with T2DM aged ≥20 years who were followed up at Shinshu University Hospital. Among those, 112 eligible individuals aged ≥65 years were included in the present study. Factors associated with 3-year changes in eGFR (ΔeGFR) and eGFR deterioration (ΔeGFR < 0) were identified using bivariate and multivariable analyses. Regarding baseline values of the subjects, the mean age was 73.5 years, mean blood pressure was 131/74 mm Hg, mean hemog

SUBMITTER: Shibata Y 

PROVIDER: S-EPMC8500559 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature