Brain volumes in adults with congenital heart disease correlate with executive function abilities.

ABSTRACT: Congenital heart disease is the most common birth defect, and patients are at risk for neurodevelopmental impairment and brain abnormalities. Yet, little is known about the link between brain volumes and cognitive function in adults with congenital heart disease. Forty-four patients and 53 controls between 18 and 32 years underwent brain magnetic resonance imaging and cognitive testing, assessed with an intelligence quotient and executive function global score. Associations between brain volumes and cognitive function were calculated using linear models. Cognitive function in patients was within the normal range (intelligence quotient: 97.74 (10.76)). Total brain volume was significantly smaller in patients compared to controls (1067.26 (113.53) vs 1113.04 (97.88) cm³, P < 0.01)

SUBMITTER: Naef N 

PROVIDER: S-EPMC8500877 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature