Ambient air pollution and posttransplant outcomes among kidney transplant recipients.

ABSTRACT: Fine particulate matter (PM_2.5 ), a common form of air pollution which can induce systemic inflammatory response, is a risk factor for adverse health outcomes. Kidney transplant (KT) recipients are likely vulnerable to PM_2.5 due to comorbidity and chronic immunosuppression. We sought to quantify the association between PM_2.5 and post-KT outcomes. For adult KT recipients (1/1/2010-12/31/2016) in the Scientific Registry of Transplant Recipients, we estimated annual zip-code level PM_2.5 concentrations at the time of KT using NASA's SEDAC Global PM_2.5 Grids. We determined the associations between PM_2.5 and delayed graft function (DGF) and 1-year acute rejection using logistic regression and death-censored graft failure (DCGF) an

SUBMITTER: Feng Y 

PROVIDER: S-EPMC8500923 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature