Short term outcomes of COVID-19 in lupus: Propensity score matched analysis from a nationwide multi-centric research network.

ABSTRACT:

Objectives

To determine the severity and outcome of COVID-19 among individuals with lupus as compared to controls. The secondary objective was to identify the risk association of sex, race, presence of nephritis, and use of various immunomodulators with COVID-19 outcomes.

Methods

Retrospective data of individuals with lupus with and without COVID-19 between January 2020 to May 2021 was retrieved from the TriNetX. A one-to-one matched COVID-19 positive control was selected using propensity score(PS) matching. We assessed several outcomes, including all-cause mortality, hospitalisation, intensive care unit (ICU) admission, mechanical ventilation, severe COVID, acute kidney injury (AKI), Haemodialysis, acute respiratory distress syndrome (ARDS), ischemic stroke, venous thromboe

SUBMITTER: Raiker R 

PROVIDER: S-EPMC8501265 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature