Complex structural variations in non-human primate hepatitis B virus.

ABSTRACT:

Background

Recent genome sequence technology has revealed a novel type of genetic rearrangement referred to as complex structural variations (SVs). Previous studies have elucidated the complex SVs in human hepatitis B viruses (HBVs). In this study, we investigated the existence of complex SVs in HBVs from non-human primates (NHPs).

Methods

Searches for nucleotide sequences of NHP HBV were conducted using the PubMed, and genetic sequences were retrieved from databases. The candidate genetic sequences harboring complex SVs were analyzed using the CLUSTALW program and MAFFT. Additional bioinformatical analyses were performed to determine strains with complex SVs and to elucidate characteristics of NHP HBV strains.

Results

One hundred and fifty-four HBV strains from NHPs

SUBMITTER: Nagura Y 

PROVIDER: S-EPMC8501659 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature