Ontology highlight
ABSTRACT:
SUBMITTER: Le Huyen KB
PROVIDER: S-EPMC8501977 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Le Huyen Kim Boi KB Gonzalez Cintia Daniela CD Pascreau Gaëtan G Bordeau Valérie V Cattoir Vincent V Liu Wenfeng W Bouloc Philippe P Felden Brice B Chabelskaya Svetlana S
Nucleic acids research 20211001 18
Staphylococcus aureus is an opportunistic human and animal pathogen with an arsenal of virulence factors that are tightly regulated during bacterial infection. The latter is achieved through a sophisticated network of regulatory proteins and regulatory RNAs. Here, we describe the involvement of a novel prophage-carried small regulatory S. aureus RNA, SprY, in the control of virulence genes. An MS2-affinity purification assay reveals that SprY forms a complex in vivo with RNAIII, a major regulato ...[more]