Anti-inflammatory effects of diet and caloric restriction in metabolic syndrome.

ABSTRACT:

Background

Weight loss in patients with metabolic syndrome has positive effects on cardiovascular and type 2 diabetes risks, but its effects on peripheral cytokines and lipid profiles in patients are still unclear.

Aim

To determine the effects of diet-induced weight loss on metabolic parameters, lipids and cytokine profiles.

Methods

Eighteen adult males with metabolic syndrome (defined according to IDF 2009) and Body Mass Index (BMI) between 25 and 35 kg/m² were subjected to a balanced hypocaloric diet for 6 months to reach at least a 5% body weight loss.

Results

After weight loss, a significant improvement in BMI, waist circumference, insulin, fasting blood glucose and HOMA-IR (homeostasis model assessment of insulin resistance) was observed. The an

SUBMITTER: Montefusco L 

PROVIDER: S-EPMC8502121 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature