The prognostic significance of [¹⁸F]FDG PET/CT in multiple myeloma according to novel interpretation criteria (IMPeTUs).

ABSTRACT:

Purpose

[¹⁸F]FDG PET/CT is the elective imaging modality for treatment monitoring in multiple myeloma (MM). However, MM is a heterogeneous disease from an imaging point of view, raising challenges in interpretation of PET/CT. We herein investigated the prognostic role of the novel Italian Myeloma criteria for PET Use (IMPeTUs) in MM patients undergoing high-dose chemotherapy (HDT) followed by autologous stem cell transplantation (ASCT).

Methods

Forty-seven patients with newly diagnosed MM underwent [¹⁸F]FDG PET/CT before commencement of treatment (baseline PET/CT). Thirty-four of them (72.3%) were also examined after completion of ASCT (follow-up PET/CT). PET/CT analysis was based on the IMPeTUs criteria, which take into consideration-among others-the m

SUBMITTER: Sachpekidis C 

PROVIDER: S-EPMC8502185 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature