Inoculation of mother's own milk could personalize pasteurized donor human milk used for feeding preterm infants.

ABSTRACT:

Background

Human milk is a vehicle for bioactive compounds and beneficial bacteria which promote the establishment of a healthy gut microbiome of newborns, especially of preterm infants. Pasteurized donor human milk (PDHM) is the second-best option when preterm mother's own milk is unavailable. Since pasteurization affect the microbiological quality of donor milk, PDHM was inoculated with different preterm milk samples and then incubated, in order to evaluate the effect in terms of bacterial growth, human milk microbiome and proteolytic phenomena.

Methods

In an in-vitro study PDHM was inoculated at 10% v/v using ten preterm milk samples. Microbiological, metataxonomic and peptidomic analyses, on preterm milk samples at the baseline (T0), on PDHM and on inoculated milk (IM) s

SUBMITTER: Mallardi D 

PROVIDER: S-EPMC8502300 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature