Exploring Peritumoral Neural Tracts by Using Neurite Orientation Dispersion and Density Imaging.

ABSTRACT: Diffusion Tensor Imaging (DTI) tractography has been widely used in brain tumor surgery to ensure thorough resection and minimize functional damage. However, due to enhanced anisotropic uncertainty in the area with peritumoral edema, diffusion tractography is generally not practicable leading to high false-negative results in neural tracking. In this study, we evaluated the usefulness of the neurite orientation dispersion and density imaging (NODDI) derived tractography for investigating structural heterogeneity of the brain in patients with brain tumor. A total of 24 patients with brain tumors, characterized by peritumoral edema, and 10 healthy counterparts were recruited from 2014 to 2021. All participants underwent magnetic resonance imaging. Moreover, we used the images obtained from t

SUBMITTER: Chong ST 

PROVIDER: S-EPMC8502884 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature