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Molecular docking analysis of human JAK2 with compounds from tomatoes.


ABSTRACT: Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) with optimal binding features with JAK2 for further consideration.

SUBMITTER: Rekha UV 

PROVIDER: S-EPMC8503773 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Molecular docking analysis of human JAK2 with compounds from tomatoes.

Rekha Umapathy Vidhya UV   Anita M M   Bhuminathan S S   Sadhana K K  

Bioinformation 20201031 10


Janus kinase 2 (JAK2) is a tyrosine kinase receptor that belongs to the JAK family kinases is linked to oral cancer. We describe the molecular binding analysis of JAK2 with 23 compounds from tomotoes. Docking data shows five compounds (rutin, qucertin, narigenin, chlrogenia acid & kaempferol) with optimal binding features with JAK2 for further consideration. ...[more]

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